Knowledge Hub
Guides on quality verification, reconstitution, and safe handling of research peptides. For laboratory research use only.
Peptide Secondary Structure and Function: Matching the Claim to the Measurement
Helix or sheet labels from free peptides or simulations do not automatically explain ice, membrane, nanoparticle, or metal-bound function.
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Interpreting potency of multi-receptor peptide agonists across assay systems
How to read multi-receptor peptide agonist EC50 values across receptors, expression systems and assays—without ranking therapeutic benefit.
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How sequence changes affect peptide proteolysis: what laboratory assays can establish
Residue swaps, N-amination, stapling and fusions can slow peptide cleavage. Score remaining peptide and remaining activity separately.
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Peptide receptor internalization: connecting trafficking to assay timing
Occupancy, endocytosis and endosomal signaling use different clocks. Three 2026 papers show why a late uptake endpoint can mis-rank peptide ligands.
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Receptor bias in peptide pharmacology: what evidence supports a signaling claim?
A peptide bias claim is a pathway comparison, not a single ratio. What 2026 GALR2, GLP-1R, and MC4R abstracts support—and omit.
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